In patients with osteoarthritis related pain sensitization of nociceptive pathways may result in patients perceiving low level stimuli as being overtly painful. In terms of clinical responses to non-pharmacological therapies, these can have an effect on supraspinal processes which influence nociceptive processing and therefore OA-related pain. This post gives a brief overview of non-pharmacological pain management strategies for osteoarthritis related hip, knee, and hand pain.