What are Myofascial Triggerpoints?

myofascial triggerpoints

From a Clinical Perspective, Myofascial Trigger Points Describe a Phenomenon

An international panel of 60 clinicians and researchers was recently consulted to establish a consensus for identification of a myofascial trigger point (MTrPs). The panel agreed on two palpatory and one symptom criteria: a taut band, a hypersensitive spot, and referred pain (Fernández-de-Las-Peñas & Dommerholt 2018).

These clinical findings may be help clinicians investigate common pain patterns, such as:
• Neck Pain (Morikawa et al. 2017)
• Migraine Headaches (Landgraf et al. 2018)
• Tension-Type Headache (Fernández-De-Las-Peñas & Arendt-Nielsen 2017)
• Carpal Tunnel Syndrome (Meder et al. 2017)
• Low Back Pain (Takamoto et al. 2015)
• Chronic Pelvic Pain (Fuentes-Márquez et al. 2018)

Sore Spots Exist, but Their Etiology is Still Not Well Understood.

It has been demonstrated that patients benefit from hands on work aimed at MTrPs, but this may not always be due to reasons we once were taught. One issue is that ascribing patient’s pain solely to MTrPs or other tissue-driven pain problem is often an oversimplification of a complex process. When it comes to MTrPs there are a number of competing hypothesis, including, but not limited to:

  • Cinderella Hypothesis - low-level, continuous muscle contractions overload tissues and makes “Cinderella” fibers susceptible to calcium dysregulation and subsequently sarcomere contracture (Bron et al. 2012).

  • Expanded Integrated Hypothesis - the zone around a MTrP seems to be in an ischemic state resulting in a shortage of glucose and oxygen for metabolism and subsequent sarcomere contracture (Gerwin et al 2004).

  • Neurogenic Inflammation - the release of inflammatory substances from the nerve axon, result in a lower the threshold for depolarization (Quintner et al. 2015).

  • Central Sensitization - several studies support the hypothesis that persistent nociceptive input from MTrP contributes to the development of central sensitization and/or changes in the dorsal horn. In contrast, preliminary evidence suggests that central sensitization can also promote MTrP activity (Fernández-de-las-Peñas et al. 2014).

The Treatment of Trigerpoints

A recent randomized, placebo-controlled trial was carried out to investigate changes in nutritive blood flow as well as glucose and lactate following massage. The researchers found there was no effect on nutritive blood flow or glucose, however there was an increase of lactate levels for massage versus sham ultrasound (Moraska et al. 2018).

So while this study found no significant changes in bloodflow, there was increase in anaerobic metabolism following the treatment. It is however important to mention, that like other massage techniques investigation into mechanisms of action should extend beyond local tissue changes and include peripheral and central pain modulation. Meaning that an observed favorable outcome may be explained by a number of overlapping responses in the periphery, spinal cord, and brain (Chimenti et al. 2018).

Stepping Back: What is the Big Picture?

The explanations used in the past of this observable phenomenon seem to be flawed in reasoning, but I do not think there is a need to abandon a  multidimensional treatment approaches that provide patients with pain relief. What is needed is an updated explanation of myofascial triggerpoints aligned with the biopsychosocial model pain.


More to Explore

SCISHOW HAS PUT TOGETHER A INSIGHTFUL VIDEO ON MYOFASCIAL TRIGGER-POINTS.

Arendt-Nielsen et al. (2016). Muscle Triggers as a Possible Source of Pain in a Subgroup of Tension-type Headache Patients? The Clinical Journal of Pain.
https://www.ncbi.nlm.nih.gov/pubmed/26550960

Bron, C. & Dommerholt, J.D. (2012). Etiology of myofascial trigger points. Curr Pain Headache Rep.
https://www.ncbi.nlm.nih.gov/pubmed/22836591

Chen et al. (2016). Quantification of Myofascial Taut Bands. Archives of Physical Medicine and Rehabilitation. Archives of Physical Medicine and Rehabilitation.
https://www.ncbi.nlm.nih.gov/pubmed/26461163

Chimenti et al. (2018). A Mechanism-Based Approach to Physical Therapist Management of Pain. Phys Ther.
https://www.ncbi.nlm.nih.gov/pubmed/29669091/

Courtney et al. (2017). Mechanisms of chronic pain - key considerations for appropriate physical therapy management. J Man Manip Ther.
https://www.ncbi.nlm.nih.gov/pubmed/28694674

Fernández-de-las-Peñas, C. & Dommerholt, J. (2014). Myofascial trigger points: peripheral or central phenomenon? Curr Rheumatol Rep.
https://www.ncbi.nlm.nih.gov/pubmed/24264721

Fernández-De-Las-Peñas, C. & Arendt-Nielsen, L. (2017). Improving understanding of trigger points and widespread pressure pain sensitivity in tension-type headache patients: clinical implications. Expert Rev Neurother.
https://www.ncbi.nlm.nih.gov/pubmed/28745080

Fernández-de-Las-Peñas, C. & Dommerholt, J. (2018). International Consensus on Diagnostic Criteria and Clinical Considerations of Myofascial Trigger Points: A Delphi Study. Pain Med.
https://www.ncbi.nlm.nih.gov/pubmed/29025044

Fuentes-Márquez et al. (2018). Trigger Points, Pressure Pain Hyperalgesia, and Mechanosensitivity of Neural Tissue in Women with Chronic Pelvic Pain. Pain Med.
https://www.ncbi.nlm.nih.gov/pubmed/29025041

Gerber et al. (2017). Beneficial Effects of Dry Needling for Treatment of Chronic Myofascial Pain Persist for 6 Weeks After Treatment Completion. PM R.
https://www.ncbi.nlm.nih.gov/pubmed/27297448

Gerwin et al. (2004). An expansion of Simons' integrated hypothesis of trigger point formation. Curr Pain Headache Rep.
https://www.ncbi.nlm.nih.gov/pubmed/15509461

Gerwin, R.D. (2018). Trigger Point Diagnosis: At Last, the First Word on Consensus. Pain Medicine.
https://www.ncbi.nlm.nih.gov/pubmed/29036664

Grosman-Rimon et al. (2017). Clinicians' perspective of the current diagnostic criteria for myofascial pain syndrome. J Back Musculoskelet Rehabil. 
https://www.ncbi.nlm.nih.gov/pubmed/27858678

Kumbhare et al. (2018). Quantitative Ultrasound Using Texture Analysis of Myofascial Pain Syndrome in the Trapezius. Crit Rev Biomed Eng. https://www.ncbi.nlm.nih.gov/pubmed/29717675

Landgraf et al. (2018). Children with migraine: Provocation of headache via pressure to myofascial trigger points in the trapezius muscle? - A prospective controlled observational study. Eur J Pain.
https://www.ncbi.nlm.nih.gov/pubmed/28952174

Nascimento et al. (2018). Inter and intraexaminer reliability in identifying and classifying myofascial trigger points in shoulder muscles. Arch Phys Med Rehabil.
https://www.ncbi.nlm.nih.gov/pubmed/28751256

Meder et al. (2017). Reliability of the Infraspinatus Test in Carpal Tunnel Syndrome: A Clinical Study. J Clin Diagn Res.
https://www.ncbi.nlm.nih.gov/pubmed/28658894

Mayoral Del Moral et al. (2018). Validity and Reliability of Clinical Examination in the Diagnosis of Myofascial Pain Syndrome and Myofascial Trigger Points in Upper Quarter Muscles. Pain Med.
https://www.ncbi.nlm.nih.gov/pubmed/29253210

Moraska et al. (2017). Responsiveness of Myofascial Trigger Points to Single and Multiple Trigger Point Release Massages: A Randomized, Placebo Controlled Trial. Am J Phys Med Rehabil. 
https://www.ncbi.nlm.nih.gov/pubmed/28248690

Moraska, A.F., Hickner, R.C., ... Kohrt, W.M. (2018). Increase in lactate without change in nutritive blood flow or glucose at active trigger points following massage: A randomized clinical trial. Arch Phys Med Rehabil.
https://www.ncbi.nlm.nih.gov/pubmed/30092205

Morikawa et al. (2017). Compression at Myofascial Trigger Point on Chronic Neck Pain Provides Pain Relief through the Prefrontal Cortex and Autonomic Nervous System: A Pilot Study. Front Neurosci. 
https://www.ncbi.nlm.nih.gov/pubmed/28442987 

Nasirzadeh et al. (2018). A Survey of Healthcare Practitioners on Myofascial Pain Criteria. Pain Pract.
https://www.ncbi.nlm.nih.gov/pubmed/29090531

Ortega-Santiago et al. (2019). Widespread Pressure Pain Sensitivity and Referred Pain from
Trigger Points in Patients with Upper Thoracic Spine Pain. Pain Med.
https://www.ncbi.nlm.nih.gov/pubmed/30821833

Palacios-Ceña et al. (2018). Trigger points are associated with widespread pressure pain sensitivity in people with tension-type headache. Cephalalgia.
https://www.ncbi.nlm.nih.gov/pubmed/27919024

Palacios-Ceña et al. (2017). Relationship of active trigger points with related disability and anxiety in people with tension-type headache. Medicine (Baltimore).
https://www.ncbi.nlm.nih.gov/pubmed/28353618

Partanen et al. (2010). Myofascial syndrome and pain: A neurophysiological approach. Pathophysiology.
https://www.ncbi.nlm.nih.gov/pubmed/19500953

Quintner et al. (2015). A critical evaluation of the trigger point phenomenon. Rheumatology.
https://www.ncbi.nlm.nih.gov/pubmed/25477053

Rathbone et al. (2017). Interrater Agreement of Manual Palpation for Identification of Myofascial Trigger Points: A Systematic Review and Meta-Analysis. Clin J Pain. 
https://www.ncbi.nlm.nih.gov/pubmed/28098584

Simons, D.G. (2008). New views of myofascial trigger points: etiology and diagnosis. Arch Phys Med Rehabil. 
https://www.ncbi.nlm.nih.gov/pubmed/18164347

Shah et al. (2015). Myofascial Trigger Points Then and Now: A Historical and Scientific Perspective. Pm&r.
https://www.ncbi.nlm.nih.gov/pubmed/25724849

Takamoto et al. (2015). Effects of compression at myofascial trigger points in patients with acute low back pain: A randomized controlled trial. Eur J Pain.
https://www.ncbi.nlm.nih.gov/pubmed/25808188

Thompson & Usichenko (2018). Pain in the hand caused by a previously undescribed mechanism with possible relevance for understanding regional pain. Scand J Pain.
https://www.ncbi.nlm.nih.gov/pubmed/29959889